A cutting-edge blood test discovered by Indiana University School of Medicine researchers could help more accurately diagnose military veterans and other people experiencing post-traumatic stress disorder, and potentially provide more precise treatments and prevention.
A study led by psychiatry professor Alexander Niculescu, MD, PhD, and published this week in the high-impact SpringerNature journal Molecular Psychiatry, tracked more than 250 veterans in over 600 visits at the Richard L. Roudebush VA Medical Center in Indianapolis to identify molecules in the blood that can help track stress intensity. The researchers used a careful four-step approach of discovery, prioritization, validation and testing. According to Niculescu’s findings, the blood test can accurately identify people who are at risk of stress disorders or are experiencing them severely.
“PTSD is a disorder that affects a lot of veterans, especially those involved in combat. They deserve our gratitude and the very best care, and we are making every effort to deliver that. It’s also an underappreciated and underdiagnosed disorder among the civilian population, whether it be the result of abuse, rape, violence or accidents” said Niculescu, who worked with other Department of Psychiatry and VA researchers on the study, as well as collaborators at The Scripps Research Institute and University of California Irvine. “Countless people are underdiagnosed with stress disorders, which may manifest themselves by drinking more, other addictions, suicide or violence. Our research has broader relevance for not just veterans but the general public.”
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Image: Dr. Alexander Niculescu and researchers in the Department of Psychiatry at Indiana University School of Medicine have developed a new blood test for PTSD. (Credit: Indiana University School of Medicine)