In recent years, giant viruses have been unearthed in several of the world’s most mysterious locations, from the thawing permafrost of Siberia to locations unknown beneath the Antarctic ice. But don’t worry, “The Thing” is still a work of science fiction. For now.
In a new study, a team of Michigan State University scientists shed light on these enigmatic, yet captivating giant microbes and key aspects of the process by which they infect cells. With the help of cutting-edge imaging technologies, this study developed a reliable model for studying giant viruses and is the first to identify and characterize several key proteins responsible for orchestrating infection.
Giant viruses are bigger than 300 nanometers in size and can survive for many millennia. For comparison, the rhinovirus — responsible for the common cold — is roughly 30 nanometers.
“Giant viruses are gargantuan in size and complexity,” said principal investigator Kristin Parent, associate professor of Biochemistry and Molecular Biology at MSU. “The giant viruses recently discovered in Siberia retained the ability to infect after 30,000 years in permafrost.”
Read more at Michigan State University
Image: Jason Schrad (left) and Kristin Parent pose next to a Talos Arctica microscope, a specialized instrument that images frozen samples to provide atomic level molecular structures. (Credit: Photo by John A. Dover)