Maternal exposure to air pollution during pregnancy has often been linked to adverse effects on the health of the newborn. However, there are very few studies on the subject. A study conducted at the UPV/EHU has just concluded in a paper published in the journal Environmental Research that the stages most sensitive to air pollution are the early and late months of pregnancy.
According to studies in recent years, air pollution affects the thyroid. Thyroid hormones are essential for regulating foetal growth and metabolism, and play an important role in neurological development. Thyroxine (T4) is the main thyroid hormone that is circulating and the thyroid-stimulating hormone is TSH. At 48 hours newborn babies undergo a heel prick test in which thyroxine and TSH levels in the blood are measured. In fact, if the balance of these thyroid hormones is not right, the risk of developing serious diseases increases. That is why, "this study set out to analyse the relationship between atmospheric pollution during pregnancy and the level of thyroxine in the newborn", explained Amaia Irizar-Loibide, a researcher in the UPV/EHU's Department of Preventive Medicine and Public Health.
Nitrogen dioxide (NO2) and fine particulate matter less than 2.5 micra in diameter (PM2.5) are two of the main pollutants related to air pollution and vehicle traffic. PM2.5 particles for example are very fine and easily enter the respiratory tract. "In this work we specifically analysed the effect of maternal exposure to these fine particles and to nitrogen dioxide during pregnancy and the link existing with thyroxine levels in newborn babies. We have been monitoring on a weekly basis, as the development of the foetus varies greatly from one week to the next. So we tried to conduct the most detailed research possible in order to find out which the most sensitive weeks of pregnancy are", added the UPV/EHU researcher.
Read more at: University of the Basque Country