Scientists have pinpointed a gene that helps deadly E. coli bacteria evade antibiotics, potentially leading to better treatments for millions of people worldwide.
The University of Queensland-led study found a particular form of the bacteria – E. coli ST131 – had a previously unnoticed gene that made it highly resistant to commonly prescribed antibiotics.
Professor Mark Schembri, from UQ’s School of Chemistry and Molecular Biosciences, said this ‘resistance gene’ can spread incredibly quickly.
“Unlike gene transfer in humans, where sex is required to transfer genes, bacteria have genetic structures in their cells – called plasmids – that are traded quickly and easily between each other,” Professor Schembri said.
“This resistance gene is in one such plasmid and is swiftly making E. coli ST131 extremely resistant to widely prescribed fluoroquinolone antibiotics.
“These antibiotics are used to treat a wide range of infections, including urinary tract infections (UTIs), bloodstream infections and pneumonia.
Read more at: The University of Queensland