Safer and more effective blood thinners could be on the way following a groundbreaking discovery by researchers at UBC and the University of Michigan, published today in Nature Communications.
By combining their expertise in blood clotting systems and chemical synthesis, the researchers have designed a new compound called MPI 8 that offers the potential to prevent blood clots without any increased risk of bleeding—a common side effect of existing blood thinners.
“The development of MPI 8 represents a major breakthrough in the field of blood clot prevention and treatment,” said Dr. Jay Kizhakkedathu, a professor and Canada Research Chair at UBC’s department of pathology and laboratory medicine and the UBC Centre for Blood Research. “By targeting a specific molecule involved in clot formation without disrupting the natural clotting process, we’ve created a blood thinner that has proven safer and more effective in animal models, with enormous potential to improve human lives as well.”
Further research will be needed to confirm the safety and efficacy of MPI 8 in humans, but initial results offer hope for a new era in blood clot prevention and thrombosis treatment while serving as a testament to the power of collaboration in research medicine.
Read more at University of British Columbia
Image Credit: Photo credit: Kizhakkedathu Research Group via University of British Columbia