Cephalopods are a large family of marine animals that includes octopuses, cuttlefish and squid. They live in every ocean, from warm, shallow tropical waters to near-freezing, abyssal depths. More remarkably, report two scientists at University of California San Diego in a new study, at least some cephalopods possess the ability to recode protein motors within cells to adapt “on the fly” to different water temperatures.
Writing in the June 8, 2023 edition of Cell, first author Kavita J. Rangan, PhD, a postdoctoral researcher in the lab of senior author Samara L. Reck-Peterson, PhD, a professor in the departments of Cellular and Molecular Medicine at UC San Diego School of Medicine and Cell and Developmental Biology at UC San Diego and an Investigator of the Howard Hughes Medical Institute, describe how opalescent inshore squid (Doryteuthis opalescens) employ RNA recoding to change amino acids at the protein level, improving the function of molecular motors that carry out diverse functions within cells in colder waters.
RNA recoding allows organisms to edit genetic information from the genomic blueprint to create new proteins. The process is rare in humans but is common in soft-bodied cephalopods, such as D. opalescens, which makes seasonal spawning migrations along the coast of San Diego.
Read more at University of California San Diego
Image: Doryteuthis opalescens, otherwise known as market squid, helped UC San Diego researchers discover the animals’ ability to recode RNA in cells to improve their functioning in different water temperatures. Credit: UC San Diego/Sea Grant California.